Publications

2023

  • Ludovica Martina Epasto, Christopher Pötzl, Herwig Peterlik, Mahdi Khalil, Christine Saint‐Pierre, Didier Gasparutto, Giuseppe Sicoli, Dennis Kurzbach: NMR‐identification of the interaction between BRCA1 and the intrinsically disordered monomer of the Myc‐associated factor X. Prot. Sci., 2023, e4849.
  • Ertan Turhan, Christopher Pötzl, Waldemar Keil, Mattia Negroni, Karel Kouřil, Benno Meier, Javier Agustin Romero, Krzysztof Kazimierczuk, Ieva Goldberga, Thierry Azaïs, and Dennis Kurzbach: Biphasic NMR of Hyperpolarized Suspensions – Real-TimeMonitoring of Solute-to-Solid Conversion to Watch Materials Grow. J. Phys. Chem. C, 2023, 127, 19591-19598.
  • Julia Kriegesmann, Thomas Schlatzer, Kateryna Che, Claudia Altdorf, Susanne Huhmann, Hanspeter Kählig, Dennis Kurzbach, Rolf Breinbauer, Christian FW Becker: Constraining and modifying peptides using Pd‐mediated cysteine allylation. ChemBioChem., 2023, e202300098.
  • Johannes Strobl, Fanny Kozak, Meder Kamalov, Daniela Reichinger, Dennis Kurzbach, Christian FW Becker: Understanding Self‐assembly of Silica Precipitating Peptides to Control Silica Particle Morphology. Adv. Mater., 2023, 16, 2207586.
  • Mattia Negroni, Dennis Kurzbach: Missing pieces in structure puzzles–How Hyperpolarized NMR can complement structural biology and biochemistry. ChemBioChem., 2023, 24, e20220070 .

2022

  • Mattia Negroni, Ertan Turhan, Thomas Kress, Morgan Ceillier, Sami Jannin, Dennis Kurzbach: Frémy’s Salt as a Low-Persistence Hyperpolarization Agent: Efficient Dynamic Nuclear Polarization Plus Rapid Radical Scavenging. J. Am. Chem. Soc., 2022, 144, 45, 20680–20686.
  • Ludovica M. Epasto, Philipp Honegger, Kateryna Che, Fanny Kozak, Florian Jörg, Christian Schröder, Dennis Kurzbach: Nuclear Overhauser spectroscopy in hyperpolarized water – chemical vs. magentic exchange. Chem. Comm., 2022, 58, 11661 – 11664.
  • Kateryna Che, Thomas Kress, Michał Górka, Szymon Żerko, Wiktor Kozminski, Dennis Kurzbach: Coupled MD simulations and NMR reveal that the intrinsically disordered domain of the breast-cancer susceptibility 1 protein (BRCA1) binds head-on to DNA double-strand ends. J. Magn. Reson. Open, 2022, DOI:10.1016/j.jmro.2022.100069.
  • Ludovica M. Epasto, Kateryna Che, Fanny Kozak, Albina Selimovic, Pavel Kaderavek, Dennis Kurzbach: Towards Protein NMR at Physiological Concentrations by Hyperpolarized Water – Finding and mapping uncharted conformational spaces. Sci. Adv., 2022, 8, eabq5179.
  • Mattia Negroni, David Guarin, Kateryna Che, Ludovica M. Epasto, Ertan Turhan, Albina Selimović, Fanny Kozak, Samuel Cousin, Daniel Abergel, Geoffrey Bodenhausen, and Dennis Kurzbach: Inversion of Hyperpolarized 13C NMR Signals through Cross-Correlated Cross-Relaxation in Dissolution DNP Experiments. J. Phys. Chem. B, 2022, 126, 24, 4599–4610.
  • Chrisitan Hilty, Dennis Kurzbach, Lucio Frydman: Hyperpolarized water as universal sensitivity booster in biomolecular NMR. Nature Protocols, 2022, 17, 1621–1657.
  • Hengxi Zhang, Carlos Modenutti, Yelha Phani Kumar Nekkanti, Maxime Denis, Iris A. Bermejo, Jonathan Lefèbre, Kateryna Che, Dongyoon Kim, Marten Kagelmacher, Dennis Kurzbach, Marc Nazaré, Christoph Rademacher: Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C‑Type Lectin Langerin. ACS Chem. Biol., 2022, DOI: 10.1021/acschembio.2c00626.

2021

  • Mattia Negroni, Dennis Kurzbach: Residue-resolved monitoring of protein hyperpolarization at sub-second time resolution. Comms. Chem., 2021, 4:147 DOI: 10.1038/s42004-021-00587-y.
  • Kateryna Che, Markus Muttenthaler, Dennis Kurzbach: Conformational selection of vasopressin upon V1a receptor binding. CSBJ, 2021, 19, 5826-5833.
  • Cornelia von Baeckmann, Guilherme M. D. M. Rubio, Hanspeter Kählig, Dennis Kurzbach, Michael R. Reithofer and Freddy Kleitz: Evaporation-induced self-assembly of small peptide-conjugated silica nanoparticles. Angew. Chem. Int. Ed., 2021, 60, 22700–22705.
  • Ludovica M Epasto, Tristan Georges, Albina Selimović, Jean-Michel Guigner, Thierry Azaïs, Dennis Kurzbach: Formation and evolution of nanoscale calcium phosphate precursors under biomimetic conditions. Analytical Chemistry, 2021, 93, 10204-10211.
  • Thomas Kress, Kateryna Che, Ludovica M. Epasto, Fanny Kozak, Mattia Negroni, Gregory L. Olsen, Albina Selimovic, and Dennis Kurzbach: A novel sample handling system for dissolution dynamic nuclear polarization experiments. Magnetic Resonance, 2021, 2, 387-394.
  • Fanny Kozak, Dennis Kurzbach: How to assess the structural dynamics of transcription factors by integrating sparse NMR and EPR constraints with molecular dynamics simulations. CSBJ, 2021, 19, 2097-2105.
  • Zoltan Dekan, Thomas Kremsmayr, Peter Keov, Mathilde Godin, Ngari Teakle,Leopold Dürrauer, Huang Xiang, Dalia Gharib, Christian Bergmayr, Roland Hellinger, Marina Gay, Marta Vilaseca, Dennis Kurzbach, Fernando Albericio, Paul F. Alewood, Christian W. Gruber and Markus Muttenthaler: Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin. Chem. Sci., 2021, 12, 4057-4063.
  • Sarah Fruehwirth, Sandra Egger, Dennis Kurzbach, Jakob Windisch, Franz Jirsa, Thomas Flecker, Miriam Ressler, Agnes T. Reiner, Nesrin Firat, Marc Pignitter: Ingredient-Dependent Extent of Lipid Oxidation in Margarine. Antioxidants, 2021, 10, 105.

2020

  • Katharina Groß, Dennis Kurzbach, Claudia Maria Angele: NMR for food profiling – Long Drink, Short Experiment: Ein interdisziplinärer Zugang zur Förderung von Urteilskompetenz. Haushalt in Bildung und Forschung, 2020, 9, 15-16.
  • Arnab Dey, Benoît Charrier, Estelle Martineau, Catherine Deborde, Elodie Gandriau, Annick Moing, Daniel Jacob, Dmitry Eshchenko, Marc Schnell, Roberto Melzi, Dennis Kurzbach, Morgan Ceillier, Quentin Chappuis, Samuel F. Cousin, James G. Kempf, Sami Jannin, Jean-Nicolas Dumez, Patrick Giraudeau: Hyperpolarized NMR Metabolomics at Natural 13C Abundance. Anal. Chem., 2020, DOI: 10.1021/acs.analchem.0c03510.
  • Giuseppe Sicoli, Thomas Kress, Hervé Vezin, Karin Ledolter, Dennis Kurzbach: A Switch Between Two Intrinsically Disordered Conformational Ensembles Modulates the Active Site of a Basic-Helix-Loop-Helix Transcription Factor. J. Phys. Chem. Lett., 2020, 11, 8944−8951.
  • Michał Górka, Szymon Żerko, Robert Konrat, Wiktor Koźmiński, Dennis Kurzbach: 1H, 13C and 15N backbone resonance assignment of BRCA1 fragment 219–504. Biomol. NMR Assignments, 2020, 14, 289–293.
  • Emmanuelle Weber, Thomas Kress, Daniel Abergel, Steffi Sewsurn, Thierry Azais, Dennis Kurzbach: Assessing the onset of calcium phosphate nucleation by hyperpolarized real-time NMR. Anal. Chem. 2020, 92, 11, 7666–7673.
  • Gregory L. Olsen, Or Szekely, Borja Mateos, Pavel Kadeřávek, Fabien Ferrage, Robert Konrat, Roberta Pierattelli, Isabella C. Felli, Geoffrey Bodenhausen, Dennis Kurzbach, Lucio Frydman: Sensitivity-Enhanced Three-Dimensional and Carbon-Detected Two-Dimensional NMR of Proteins using Hyperpolarized Water. J. Biomol. NMR, 2020, 74, 161–171.
  • Alaz Özcan, Dilara Sahin, Daniela Impellizzieri, Tuan T. Nguyen, Jürg Hafner, Nikhil Yawalkar, Dennis Kurzbach, Ge Tan, Cezmi A. Akdis, Jakob Nilsson, Onur Boyman, Antonios G.A. Kolios: Nanoparticle-coupled topical methotrexate can normalize immune responses and induce tissue remodeling in psoriasis. J. Investigative Dermatology, 2020, 140, 1003-1014.e8.

2019

  • Aude Sadet, Cristina Stavarache, Mihaela Bacalum, Mihai Radu, Geoffrey Bodenhausen, Dennis Kurzbach, Paul R. Vasos: Hyperpolarized water enhances two-dimensional proton NMR correlations: a new approach for molecular interactions. J. Am. Chem. Soc. 2019, 32, 12448-12452.
  • Emmanuelle Weber, Dennis Kurzbach, Daniel Abgergel: A DNP-hyperpolarized solid-state water NMR MASER: observation and qualitative analysis. Phys. Chem. Chem. Phys. 2019, 21, 21278-21286.
  • Aleksey Kiryutin, Bogdan A. Rodin, Alexandra V. Yurkovskaya, Konstantin L. Ivanov, Dennis Kurzbach, Sami Jannin, David Guarin, Daniel Abergel, G Bodenhausen: Transport of hyperpolarized samples in dissolution-DNP experiments. Phys. Chem. Chem. Phys. 2019, 21, 13696-13705.
  • Sami Jannin, Jean-Nicolas Dumez, Patrick Giraudeau, Dennis Kurzbach: Application and methodology of dissolution dynamic nuclear polarization in physical, chemical and biological contexts. J. Magn. Reson. 2019, 305, 41-50.
  • Giuseppe Sicoli, Hervé Vezin, Karin Ledolter, Thomas Kress, Dennis Kurzbach: Conformational tuning of a DNA-bound transcription factor. Nucl. Acids. Res. 2019, 47, 5429-5435.
  • Thomas Kress, Astrid Walrant, Geoffrey Bodenhausen, Dennis Kurzbach, Long-lived States in Hyperpolarized Deuterated Methyl Groups Reveal Weak Binding of Small Molecules to Proteins. J. Phys. Chem. Lett. 2019, 10, 7, 1523-1529.

2018

  • Pavel Kaderavek, Fabien Ferrage, Geoffrey Bodenhausen, Dennis Kurzbach: High‐Resolution NMR of Folded Proteins in Hyperpolarized Physiological Solvents. Chem. Eur. J. 2018, 24, 13418-13423.
  • Konstantin L. Ivanov, Thomas Kress, Mathieu Baudin, David Guarin, Daniel Abergel, Geoffrey Bodenhausen, Dennis Kurzbach: Relaxation of long-lived modes in NMR of deuterated methyl groups. J. Chem. Phys. 2018, 149, 054202.
  • Andreas Beier, Thomas C. Schwarz, Dennis Kurzbach, Gerald Platzer, Francesca Tribuzio, Robert Konrat: Modulation of Correlated Segment Fluctuations in IDPs upon Complex Formation as an Allosteric Regulatory Mechanism. J. Mol. Biol. 2018, 16, 2439-2452.
  • Aude Sadet, Emmanuelle Weber, Aditya Jhajharia, Dennis Kurzbach, Geoffrey Bodenhausen, Emeric Miclet, Daniel Abergel: Kinetic rates of chemical metabolic processes determined by NMR boosted by dissolution dynamic nuclear polarization. Chem. Eur. J., 2018, 24, 5456-5461.
  • Emmanuelle M. M. Weber, Guiseppe Sicoli, Hervé Vezin, Ghislaine Frébourg, Daniel Abergel, Geoffrey Bodenhausen, Dennis Kurzbach: Sample Ripening through Nanophase Separation Boosts Influences Dynamic Nuclear Polarization. Angew. Chem. Int. Ed., 2018, 130, 5267-5271.

2017

  • David Guarin, Sina Marhabaie, Alberto Rosso, Daniel Abergel, Geoffrey Bodenhausen, Konstantin L. Ivanov, Dennis Kurzbach: Characterizing Thermal Mixing via the Cross Talk between Spin Reservoirs, J. Phys. Chem. Lett., 2017, 8, 5531-5536.
  • Ludmilla Guduff, Dennis Kurzbach, Carine van Heijenoort, Daniel Abergel, Jean-Nicolas Dumez: Single-scan 13C diffusion-ordered NMR spectroscopy of DNP-hyperpolarised substrates Chem. Eur. J., 2017, 23, 16722-16727.
  • Gönül Kizisavas, Karin Ledolter, Dennis Kurzbach: Hydrophobic Collapse of the Intrinsically Disordered Transcription Factor MAX. Biochemistry, 2017, 56, 5365-5372.
  • Emmanuelle Weber, Daniel Abergel, Hervé Vezin, Geoffrey Bodenhausen, Dennis Kurzbach: Anisotropic Longitudinal Electronic Relaxation Affects DNP at Cryogenic Temperatures. Phys. Chem. Chem. Phys, 2017, 19, 16087-16094.
  • Dennis Kurzbach, Andreas Beier, Agathe Vanas, Andrea G. Flamm, Gerald Platzer, Thomas C. Schwarz, Robert Konrat: NMR Probing and Visualization of Correlated Structural Fluctuations in Intrinsically Disordered Proteins. Phys. Chem. Chem. Phys, 2017, 19, 10651-10656.
  • Aditya Jhajharia, Emmanuelle M. M. Weber, James G. Kempf, Daniel Abergel, Geoffrey Bodenhausen, Dennis Kurzbach: Dissolution DNP Reveals a Long-Lived Deuterium Spin State Imbalance in Methyl Groups. J. Chem. Phys. 2017, 146, 041101.
  • Dennis Kurzbach, Estel Canet, Andrea G. Flamm, Aditya Jhajharia, Emmanuelle M. M. Weber, Robert Konrat, and Geoffrey Bodenhausen: Investigation of Intrinsically Disordered Proteins by Exchange with Hyperpolarized Water. Angew. Chem. Int. Ed. 2017, 56, 389-392.

ALL PUBLICATIONS